Toshihiko Hanada, Maulana A. Empitu, Gregory I. Mines,1 Qianni Ma, Iziegbe L. Omorodion, Ansel Link,1 Christopher J. Schwake, Rachel M. Krueger, Nicholas S. DaRosa, Andrew E. Levin, Edouard Vannier, Athar H. Chishti. Identification of Babesia microti immunoreactive antigens by phage display cDNA screen. Infection and Immunity 2024 Jul 11;92(7):e0021524. https://doi.org/10.1128/iai.00215-24

Christopher J. Schwake, Rachel M. Krueger, Toshihiko Hanada, and Athar H. Chishti. Plasmodium falciparum Glutamic Acid-Rich Protein-Independent Polyclonal Antibodies Inhibit Malaria Parasite Growth in Human Erythrocytes. J Infect Dis. 2024 May 15;229(5):1565-1573.

Erin D Lewis, Edwin F Ortega, Maria Carlota Dao, Kathryn Barger, Joel B Mason, John M Leong, Marcia S Osburne, Loranne Magoun, Felix J Nepveux V, Athar H Chishti, Christopher Schwake, Anh Quynh, Cheryl H Gilhooly, Gayle Petty, Weimin Guo, Gregory Matuszek, Dora Pereira, Manju Reddy, Jifan Wang, Dayong Wu, Simin N Meydani, Gerald F Combs Jr. Safe and effective delivery of supplemental iron to healthy adults: a two-phase, randomized, double-blind trial – the safe iron study. Front Nutr. 2023 Oct 11:10:1230061.

Daniel I Fritz, Yiwen Ding, Glenn Merrill-Skoloff, Robert Flaumenhaft, Toshihiko Hanada, Athar H Chishti. Dematin Regulates Calcium Mobilization, Thrombosis, and Early Akt Activation in Platelets. Mol Cell Biol. 2023;43(6):283-299. 2023 May 22.

Schwake C, McKay L, Griffiths A, Scartelli C, Flaumenhaft R, Chishti AH. BDA-410 inhibits SARS-CoV-2 main protease activity and viral replication in mammalian cells. J Cell Mol Med. 2022 Sep 9. doi: 10.1111/jcmm.17442. Epub ahead of print. PMID: 36082511.

Zhou R, Han B, Nowak R, Lu Y, Heller E, Xia C, Chishti AH, Fowler VM, Zhuang X. Proteomic and functional analyses of the periodic membrane skeleton in neurons. Nat Commun. 2022 Jun 9;13(1):3196. doi: 10.1038/s41467-022-30720-x. PMID: 35680881; PMCID: PMC9184744.

Schwake C, Hyon M, Chishti AH (2022). Signal peptide peptidase: a potential therapeutic target for parasitic and viral infections. Expert Opinion on Therapeutic Targets. 7:1-13. doi: 10.1080/14728222.2022.2047932. Epub ahead of print. PMID: 35235480.

Mithila F, Schwake C, Fang C, Merrill-Skoloff G, Covic L, Fritz DI, Hanada T, Flaumenhaft R, Chishti AH (2022). Calpain-1 inhibition attenuates in vivo thrombosis in a humanized model of sickle cell disease. Thrombosis Research 4;211:123-126. doi: 10.1016/j. Epub ahead of print. PMID: 35149397.

Almukadi, H., Schwake, C., Kaiser, M., Mayer, G., Schiemer. J., Baldwin, M., Hegde, S., Lu, Y., Hanada. T., and Chishti, A.H. (2019). Human erythrocyte band 3 is a host receptor for Plasmodium falciparum glutamic acid-rich protein. Blood 133:470-480. PMID: 30545833 PMCID: PMC6356982.

Schwake. C., Baldwin., M.R., Bachovchin, W., Hegde, S., Schiemer. J., Okure, C., Levin. A.E., Vannier, E., Hanada, T., and Chishti, A.H. (2019). HIV protease inhibitors block parasite signal peptide peptidases and prevent growth of Babesia microti parasites in erythrocytes. Biochemical and Biophysical Research Communications 517: 125-131.

Fritz, D.I., Hanada, T., Lu, Y., Johnston, J. M., and Chishti, A.H. (2019). MPP1/p55 gene deletion in a hemophilia A patient with ectrodactyly and severe developmental defects. American Journal of Hematology 94: E29-E32. PMID: 30358901.

Nwankwo, J.O., Gremmel, T, Gerrits, A.J., Mithila, F.J., Warburton, R.J., Hill, N.S., Lu, Y., Richey, L.J., Jakubowski, J.A., Frelinger, A.L., and Chishti, A.H. (2017). Calpain-1 regulates platelet function in a humanized mouse model of sickle cell disease. Thrombosis Research 160:58-65. PMID: 29101791 PMCID: PMC5723238.

Nwankwo, J.O., Lei, J., Xu, J., Rivera, A., Gupta, K., Chishti, A.H. (2016). Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease. Haematologica 101:397-400. PMID: 27418647; PMCID: PMC5046659

Baldwin, M.R., Li, X., Hanada, T., Liu, S-L., and Chishti. A.H. (2015). Merozoite surface protein 1 recognition of host glycophorin A mediates malaria parasite invasion of red blood cells. Blood 125:2704-2711. PMID: 25778531; PMC4408295

Baldwin, M., Yamodo, I., Ranjan, R., Li, X., Mines, G., Marinkovic. M., Hanada, T., Oh, S.S., and Chishti, A.H. (2014). Human erythrocyte Band 3 functions as a receptor for the sialic acid-independent invasion of Plasmodium falciparum. Role of the RhopH3-MSP1 complex. Biochimica et Biophysica Acta-Molecular Cell Research 1843:2855-70. PMID: 25157665

Franceschi, L.D., Franco, R.S., Bertoldi, M., Brugnara, C., Matte, A., Siciliano, A., Wieschhaus, A.J., Chishti, A.H., and Joiner, C.H. (2013). Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease. FASEB Journal 27:750-759.

Wieschhaus, A., Khan, A., Zaidi, A., Rogalin, H., Hanada, T., Liu, F., Franceschi, L.D., Brugnara, C., Rivera, A., and Chishti, A.H. (2012). Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology. Biochemical Journal 448: 141–152.

Kuchay, S.M., Wieschhaus, A.J., Marinkovic, M., Herman, I.M., and Chishti. A.H. (2012). Targeted Gene Inactivation Reveals a Functional Role of Calpain-1 in Platelet Spreading. Journal of Thrombosis and Haemostasis 10:1120-32.

Quinn BJ, Welch EJ, Kim AC, Lokuta MA, Huttenlocher A, Khan AA, Kuchay SM, Chishti AH. Erythrocyte scaffolding protein p55/MPP1 functions as an essential regulator of neutrophil polarity. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19842-7. doi: 10.1073/pnas.0906761106. Epub 2009 Nov 6. PMID:19897731; PMCID: PMC2785254.

Li, X., Chen, H., Oh, S.S., Chishti, A.H. (2008). A Presenilin-like protease associated with Plasmodium falciparum micronemes is involved in erythrocyte invasion. Molecular Biochemical Parasitology 158:22-31.

Kuchay, S.M., Kim, N., Grunz, E.A., Fay, W.P., and Chishti, A.H. (2007). Double Knockouts reveal that Protein Tyrosine Phosphatase 1B is a Physiological Target of Calpain-1 in Platelets. Molecular Cell Biology 27, 6038-6052.